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Chronic elevated cortisol promotes abdominal fat storage and interferes with sleep (which further promotes weight gain)

However, to get further insight in the role of SLC35A39 in the brain, the generation of specific conditional Slc25a39 knockout mice that carry a deletion of Slc25a39 exclusively in neurons or in the central nervous system may further boost our understanding on the roles and in the importance of SLC25A39 in neuronal tissues